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Body’s cancer defences hijacked to make pancreatic and lung cancers more aggressive

Researchers have discovered that a vital self-destruct switch in cells is hijacked – making some pancreatic and non small cell lung cancers more aggressive, according to a report in Cancer Cell.

Researchers have discovered that a vital self-destruct switch in cells is hijacked – making some pancreatic and non small cell lung cancers more aggressive, according to a report in Cancer Cell. The team, from the Cancer Research UK Centre at the UCL (University College London) Cancer Institute, found that mutations in the KRAS gene interferes with protective self-destruct switches, known as TRAIL receptors, which usually help to kill potentially cancerous cells. The research, carried out in cancer cells and mice, shows that in cancers with faulty versions of the KRAS gene these TRAIL receptors actually help the cancer cells to

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