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The main psychoactive ingredient of cannabis can cause short-term paranoia, according to the results of a study. This study, funded by the Medical Research Council (MRC), is the most in-depth investigation ever of the paranoia-inducing effects of the main psychoactive ingredient in cannabis, THC (9-tetrahydrocannabinol) and also identified psychological factors that can lead to feelings of paranoia in people who take cannabis. The team of researchers, led by Professor Daniel Freeman, MRC senior clinical fellow at the University of Oxford, found that worrying, low self-esteem, anxiety, depression and experiencing a range of unsettling changes in perceptions most likely led to
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