Diabetes in writingRyzodeg (insulin degludec/insulin aspart) delivers significantly lower rates of hypoglycaemia and nocturnal hypoglycaemia in a broad range of type 2 diabetes patients, new research has revealed.

The analyses found that insulin degludec/insulin aspart achieved successful glycaemic control with significantly lower rates of hypoglycaemia and nocturnal hypoglycaemia in patients with type 2 diabetes versus BIAsp 30 and/or a basal-bolus regimen of insulin degludec and insulin aspart.

The findings were presented yesterday (1 December) at the 23rd World Diabetes Congress of the International Diabetes Federation.

Researchers looked at pooled data from 5 clinical studies, which highlighted that these benefits were delivered to patients irrespective of baseline HbA1c, disease duration or BMI. The results also revealed that use of insulin degludec/insulin aspart resulted in statistically significant reductions in fasting plasma glucose, and a lower insulin dose with significant differences in patients with BMI ≤30 or a disease duration longer than 10 years against its comparators.

“Managing hypoglycaemia while also achieving optimal glycaemic control are important considerations when selecting a treatment regimen,” said Dr Helena Rodbard, presenting author of the analyses. “These findings are especially relevant in the era of personalised medicine, and provide valuable assistance to the clinical use of Ryzodeg in patients with type 2 diabetes.”

These data are from the analyses of 5 26-week treat-to-target phase 3a/b clinical trials in people with type 2 diabetes.