Investigation into GLP-1 based diabetes therapies concluded

The Committee for Medicinal Products for Human Use (CHMP) has finalised a review of GLP-1-based diabetes therapies. The Committee concluded that presently available data do not confirm recent concerns over an increased risk of pancreatic adverse events with these medicines.  The rise of type-2 diabetes is a major public health challenge. GLP-1 based therapies are effective treatments for type-2 diabetes and add to the available medication options. The term GLP-1 based therapies comprises two classes of medicines: glucagon-like-peptide-1 (GLP-1) agonists and dipeptidylpeptidase-4 (DPP-4) inhibitors.  The review of these medicines was initiated following the publication of a study by a group